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During a calorie deficit, recovery is compromised

However, Clare Thompson, a general practitioner and lead of the weight management service at Cadogan Clinic in the United Kingdom, further noted the studys limitations

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76 Thus, since PI3K/Akt is activated by both cAMP-dependent and cAMP-independent pathways, there is likely context-dependent variability in GLP-1R signaling, influenced by cell type, receptor architecture, and duration of stimulation

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[DOI] [PMC free article] [PubMed] [Google Scholar] Beak SA, Heath MM, Small CJ, Morgan DG, Ghatei MA, Taylor AD, Buckingham JC, Bloom SR, Smith DM