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Options include: Returning to the previous dose: If heartburn appeared at 10mg but was absent at 7.5mg, stepping back to 7.5mg for a longer period before attempting escalation again often works

Novo is expanding its manufacturing footprint to resolve supply constraints, which should strengthen scalability and support global distribution

Supports long-term weight management by decreasing body mass index (BMI)

Seek urgent medical help (call 111 or 999) if you have very high blood glucose readings (above 20 mmol/L), feel unwell with symptoms of dehydration, confusion, or vomiting, or have positive ketones if you've been advised to test for these

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Why Semaglutide May Cause Temperature Sensitivity GLP-1 activation influences appetite centers in the hypothalamus, the brain region that also regulates core body temperature and thermoregulation