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A prospective, randomised, controlled, multi-centre comparative effectiveness study of healing using dehydrated human amnion/chorion membrane allograft, bioengineered skin substitute or standard of care for treatment of chronic lower extremity diabetic ulcers

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But nowadays, it has been used by people as an addiction, and its excessive use can cause cancer

PLoS One 9:e111580 Huang LZ, Abbott LC, Winzer-Serhan UH (2007) Effects of chronic neonatal nicotine exposure on nicotinic acetylcholine receptor binding, cell death and morphology in hippocampus and cerebellum

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