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Hassan MS, Lau RWM (2009) Effect of particle shape on dry particle inhalation: study of flowability, aerosolization, and deposition properties

Millward DJ, Smith K

Pros and Cons Benefits: Proven reduction in HbA1c and cardiovascular risk in diabetic patients Significant, sustained weight loss observed in clinical trials Once-weekly dosing improves adherence compared to daily medications Minimal impact on heart rate at therapeutic doses Drawbacks: Common side effects include nausea, vomiting, diarrhea, and constipation, especially during dose escalation Potential risk of pancreatitis, gallbladder disease, and suicidal thoughts (rare) High cost without insurance

d Mean change in BMI does not equal to 3.7 kg/m 2 because the change was calculated for only 321 out of 343 patients

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Temperature changes on Wegovy are usually subtle rather than extreme
