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Safety considerations include assessing for potential complications from the original surgery, ensuring adequate nutritional status, and evaluating kidney and liver function

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However, clinical data suggests that without proper monitoring, a significant portion of that weight loss can come from lean tissue

Tiansheng Wang, the University of North Carolina at Chapel Hill, and colleagues examined the association of DR with GLP-1RAs as well as with other glucose-lowering drugs, glucose-lowering drugs excluding insulin, 2 classes of therapeutic alternatives (thiazolidinediones and SGLT2 inhibitors), SGLT2 inhibitors alone, and all other drugs in the database
