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Dark urine is not listed as a recognised side effect in UK regulatory documentation (MHRA/EMA), but occurs secondarily through dehydration mechanisms

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The July 2026 paper is a laboratory formulation study

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We note that the magnitude of weight loss in this study was less than that observed in the general population with obesity or overweight from the randomized trials of incretin-based weight loss medications with lifestyle that report roughly 816% average weight loss in 6 months after initiation [16, 17]