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10.1093/oxfordjournals.jbchem.a124894 J
Images were obtained using a DragonFly confocal imaging system (Andor)
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Tryptophan serves as a critical amino acid in this context, being primarily metabolized through the kynurenine pathway during inflammatory responses due to the activity of indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) 51,52
doi:10.1016/j.cmet.2016.05.006 Yoshino J, Mills KF, Yoon MJ, Imai SI
Although the underlying mechanism remains unclear, several hypotheses may explain this effect
