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Our goal is to offer novel insights into the optimization of bone health management in the context of weight loss, guided by a translational medicine perspective.

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While the overall frequency of liver enzyme elevations across the over 1,400 participant safety database of danuglipron is in-line with approved agents in the class, a single asymptomatic participant in one of the dose-optimization studies experienced potential drug-induced liver injury which resolved after discontinuation of danuglipron

P=0.001] and whole-body bone mineral density [MD0.02 kg/m2 (95% CI,0.04 to0.00)