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The 12% body weight loss during the weight loss phase led to marked decreases in plasma leptin and free leptin index levels and significant increase in soluble leptin receptor levels, confirming previous findings regarding the effect of weight loss on leptin activity

Compared directly with other second-line antidiabetic medications, semaglutide was again associated with better mental health outcomes, suggesting its benefits extend beyond glucose control alone

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[DOI] [PubMed] [Google Scholar] 661.Gutzwiller J.P., Tschopp S., Bock A., Zehnder C.E., Huber A.R., Kreyenbuehl M