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Studies were excluded if they met at least one of the following exclusion criteria: (1) non-primary research (e.g., review articles, commentaries, letters to the editor, dissertations, protocols, published abstracts), (2) case reports or case series, (3) does not use a GLP-1 receptor agonist as an intervention, and (4) does not report on glutamatergic or NMDA/AMPA receptor activity

Can I switch to Wegovy if my BMI is below 27

GLP1-RAs and SGLT2is are effective in treating T2D by different mechanisms

Several GLP-1 receptor agonists are currently licensed for use in the UK, including semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), exenatide (Bydureon BCise), and lixisenatide (Lyxumia)

doi: 10.1016/j.diabres.2021.109146

The cold temporarily numbs the surface nerve endings