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[19] [20] XPCS and TTD fibroblasts from ERCC2 (XPD) mutant human and mouse show evidence of defective repair of oxidative DNA damages that may underlie the segmental progeroid (premature aging) symptoms [21] (see DNA damage theory of aging)

Erythroid differentiation regulator 1, an interleukin 18-regulated gene, acts as a metastasis suppressor in melanoma

GLYIKO cells also showed a slow growth pattern however GLYIIKO cells maintained a steady growth comparable to the wild type yeast cells

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The production of ROS is linked to the overexpression of a misfolded disulphidebonded protein, carboxypeptidase Y (CPY * )