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Mendelian randomization analysis also showed an inverse relationship between GLP-1 receptor expression and severe DR, indicating the potential of GLP-1RAs in reducing the risk of DR in type 2 diabetes patients (Zheng et al., 2023)
Availability of data and materials: No data were used for the research described in the article
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Overall, changes in AQP4 and Cx43 were unidirectional across all groups
Berberine, by contrast, activates an enzyme called AMP-activated protein kinase (AMPK), which acts as a metabolic switch affecting glucose processing and fat storage in cells