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Regulatory or tolerogenic DCs are particularly important especially in the context of maintaining self-tolerance in a healthy state
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Taken together, hyperhomocysteinemia through activation of NF-B and NLRP3 inflammasome signaling pathways may augment PD neuropathology and associated neuroinflammation

A pharmacokinetic tracking study reported that LBPs are not easily absorbed in the body and are slowly eliminated through urine and faeces, with a cumulative excretion rate of 92.27% within 72 h after 50 mg/kg LBPs intake [27], thus indicating a longer stagnation in the large intestine
