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Description
When the cells are exposed to oxidative stress, NRF-2 escapes the negative regulation of KEAP1 through the increase of NRF-2, the transcription of interleukins decreases the levels of antioxidant response elements increase
The implication of other kinases than GRK and PKC in MOR desensitization was also investigated

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Illustrative examples include L
Renal involvement is frequent in classic male Fabry disease, as well as a renal variant of nonclassical female Fabry disease 8

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