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Initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin for patients with Type 2 diabetes mellitus

doi: 10.1016/0742-8413(94)00087-q

In appropriate candidates, GLP-1s have also been shown to lower A1C, reduce BMI, and decrease cardiovascular risk

Nature (2006) 444(7121):8607.10.1038/nature05485 6 NielsenSTJanumSKrogh-MadsenRSolomonTPMllerK

and (c) FDA-approved products containing semaglutide are available

For that reason, preconception planning should include nutrition and lifestyle support, close blood sugar monitoring when needed, and a realistic plan to maintain as much of the health benefit as possible after stopping the medication