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However, the majority of polyphenols reach the colon, where the diverse and abundant microbial community, including Bacteroidetes and Firmicutes , further metabolizes them into bioactive compounds of physiological importance

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Additionally, the level of 4-hydroxynonenal (4-HNE) is markedly higher in migraine patients compared to controls, further supporting the presence of oxidative stress (Table 1)

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A subset of subjects were given oral heavy isotopelabeled l-carnitine challenge testing as outlined below

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The Cognitive-Enhancing Outcomes of Caffeine and L-theanine: A Systematic Review

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NEC, Necrotizing enterocolitis

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