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Traditional smoking cessation aids, such as nicotine replacement therapy (NRT), prescription medications like varenicline or bupropion, and behavioral therapies, have been proven effective in helping individuals quit smoking

Brain-derived neurotrophic factor (BDNF) is important for neurogenesis, and various depressive symptoms arise from decreased BDNF levels (Sahay and Hen, 2007)

Felson, an arthritis expert and professor of medicine at Boston University School of Medicine, said the study changes the landscape, adding that the pain reduction is greater than anything that can be achieved short of knee replacement surgery

What factors should researchers consider when evaluating these compounds

72.3%, SMD = 0.006)