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3 The clinical onset of metabolic mediated neurodegenerative disease Given the ability of DM to lead to aging processes tied to oxidative stress, neuronal and vascular injury, mitochondrial dysfunction, stem cell loss, and immune system disorders, it becomes evident that loss of metabolic homeostasis with DM can result in multiple neurodegenerative disorders

2016 Anawalt, BD

V., Tardieu, G

Eur J Biochem 191:483489, 1990

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