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In a disorder defined by symptoms related to fatigue, autonomic nervous system problems [e.g., ( By using brainstem-specific spatial registration in addition to standard neocortex spatial registration, neuroimaging studies of ME/CFS are much more likely to detect any functional and structural abnormalities that may be driving autonomic and neuroimmune-related symptoms

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This hypothesis, based originally to a large extent on early pharmacological findings with antipsychotics [5,6,7], postulates that psychotic symptoms are attributed to the hyperactivity of dopaminergic neurons in the mesolimbic pathway [4]

We ignore the canalicular transport into the bile because it is a relatively small percentage of total export [33]