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McCleery J, Abraham RP, Denton DA, et al

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A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase

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Overall, preclinical studies have shown that NAD + and mitochondrial metabolism play a crucial and intertwined role in aging and age-associated diseases, as well as being possible therapeutic targets for ameliorating these conditions