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the hypothesized linkage between the action of AngFV analogues and the HGF/c-Met system predicted that like Dihexa and Nlel -AnglV HGF should be able to stimulate dendritic spine growth in dissociated hippocampal neurons
In consistent with the results of the cell-based activity assay, our in vitro pull-down assay results showed that the HGF E159R mutant exhibited significantly lower binding affinity to the c-MET, as compared with wild-type HGF (Figs
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