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Physician-guided programs designed to support long-term results.

Based on this review, evidence from head-to-head and insulin-comparator trials demonstrates that dual GIP/GLP-1 co-agonism consistently overcomes metabolic plateaus that result from single-pathway therapy, producing superior glycated hemoglobin reduction, bariatric-level weight loss (up to 25.3%), and robust macrovascular and heart failure protection, including a 38% reduction in composite cardiovascular risk among patients with heart failure with preserved ejection fraction (HFpEF)

Diabetes GLP-1s perform better but still leak demand: Diabetes-indicated GLP-1s show higher retention (24% at one year) and face fewer access hurdles due to broader coverage and disease framing, yet 76% of demand remains unmet

Figure 1 shows some key examples of the types of digital solutions currently being used for weight management, including the top-rated apps for weight disorders according to IQVIAs AppScript Digital Medicine Database, and insights from in-depth interviews that IQVIA has conducted with people living with obesity in the US, UK and Spain on how digital solutions are currently being used (IQVIAs Obesity Patient Voice Book of Insights2).

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