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Monitor cognition and brain health : If using GLP-1 agents, baseline cognitive testing (memory, executive function) and periodic follow-up may help document whether there is slowing of decline (though in routine practice, this is limited)

See cited studies for primary sources

Chronic diarrhea often points to a more serious condition, like irritable bowel syndrome, or a persistent infection, like inflammatory bowel disease

Addressing and reducing side effects is a pivotal aspect of medical treatments and the advancement of new pharmaceuticals [41, 42]

The drugs also seem to reduce inflammation, which may help to reduce risk of cancer

Retatrutide adds glucagon receptor activation to the dual GLP-1/GIP activation that tirzepatide provides