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Nature Medicine Al-Aly et al
doi: 10.1016/j.ebiom.2023.104642
However, the AUC of the victim drugs were not altered by GLP-1 RA administration in most cases, suggesting that clinically significant DDIs are unlikely to occur

Semaglutide (Ozempic, Wegovy, Rybelsus) Semaglutide comes in three brand names with different uses and delivery methods: is Ozempic approved for improving blood sugar control in adults with type 2 diabetes, and for reducing the risk for heart problems and end-stage kidney disease in those with diabetes

It is also worth noting that GLP-1s cardioprotective effects act independently of weight loss with a higher expression level of cardio-protective genes, including Akt, GSK3b, PPARD and so on (103)
Risk of stability and dosing accuracy GLP-1 receptor agonist medications are typically available in pre-filled injection form to deliver a precise dose
