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These results demonstrate the potential of GLP-1RAs not only to promote weight loss and metabolic improvement but also to act directly on the hypothalamic inflammation
Tirzepatide engages both GIP and GLP-1 receptors
100% of patients in the highest dose group lost at least 5% of their starting weight, and approximately 75% lost more than 15%
Molecular & Cellular Proteomics: MCP, 16 (7), 1286-1296
