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The mechanism underlying these opposing gastrointestinal effects likely relates to semaglutides complex effects on gastrointestinal motility, with some patients experiencing accelerated intestinal transit while others experience overall slowing of gastrointestinal motility

In fact, it was approved by the Food and Drug Administration (FDA) for fibromyalgia in 2008

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Expert Review of Clinical Pharmacology, 14(2), 151160
If we think of Reconstruction very broadly as a time period in which the federal government is attempting to rebuild physically like infrastructure, building railroads but also politically and trying to really change the nation to encompass new Black citizenry