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Background Inflammation is a common pathological phenomenon of osteoarthritis (OA)

In this piece, I share why most GLP-1 contracts reward the wrong outcome, the three commercial models that dominate this market, and where each one has an opportunity to improve, and how Twin built a commercial model that finally puts the vendor's incentives on the same side as yours.

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The GLP-1 NAION vision-loss MDL hit 146 cases on the July JPML report up 70% in two months as the GI-injury MDL heads to Rule 702 hearings September 10-18.

New GLP-1 pill helps patients lose up to 8% of body weight, trial shows Orforglipron led to greater weight loss than semaglutide tablets and could offer more effective oral alternative to jabs A new daily pill could be a more effective GLP-1 tablet for weight loss, according to a clinical trial that may pave the way for an improved non-injection alternative to Wegovy and Mounjaro

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