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This multi-pathway approach triggers a more comprehensive metabolic reset than single-receptor medications, which is why clinical trials show superior weight-loss outcomes at equivalent timepoints

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Following any potential approval, health technology appraisal bodies would evaluate the drug's clinical and cost-effectiveness before recommending its use within NHS services: this includes NICE for England, the Scottish Medicines Consortium (SMC) for Scotland, and the All Wales Medicines Strategy Group (AWMSG) for Wales
