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Furthermore, regulation of astrocytic mitochondrial function and redox status by IGF1 is essential to maintain astrocytic function and coordinate hippocampal-dependent spatial learning (Logan et al., 2018)

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For instance, the MNA levels in serum were found increased in the obese people [22] and the MNA levels in urine were found increased both in obese db/db mice and in obese Zucker rats [21]