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However, meta-analysis encompassing eight CVOTs showed positive impact of GLP-1 receptor agonists on heart failure in patients with type 2 diabetes (T2D)

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BMJ Glob Health

Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population

& Reboucas, N

It augments the effects of insulin on its cellular targets (especially in the adipose tissue) and has shown cardiovascular benefits in randomized controlled trials (RCTs), meta-analyses of several prospective studies and large observational studies [45, 46]