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In 2013, just as cigarette prices were going through an increase, the retailer introduced Crown cigarettes as part of an effort to provide a low-price alternative with a strong margin

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Additionally, the presence of macrophages in triple-culture models further amplified the inflammatory response, highlighting the crucial role of immune cells in mediating lung injury scenarios

The three regions (Europe A and C and Americas D) were excluded, as these were not among those regions included in the INTERHEART study (Additional file 1: Appendix 4)