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In vitro study found that neither nicotine nor cotinine in low concentration (1 mmol l 1 ) were conclusively harmful to sperm motility, but a higher nicotine concentration (1 mmol l 1 ) decreased the sperm motion and viability parameters significantly.6 Condorelli et al .7 reported that nicotine suppressed sperm progressive motility in a concentration-dependent manner starting from the relative low concentration (1 ng ml 1 ) in vitro

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