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Further analyses have revealed that post-transcriptional gene silencing occurred in this and many other cases (Waterhouse et al

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33 There is solid evidence from animal studies and in vitro studies that metabolically activated PAH bind to DNA and cause mutations in TP53 and KRAS , as indicated in Figure 1

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For cases in which the gingivitis has become chronic, aggressive, or has been diagnosed as acute necrotizing ulcerative gingivitis (ANUG) or juvenile gingivitis, a periodontist may be needed to help treat and reverse the disease