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Taking together the existing evidence, potential mechanisms including a positive feedback loop of smoking and the potential role of neurotransmitter-associated metabolic biomarkers therein were revealed

Serum cotinine levels could not be estimated

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Exposure to point-of-sale marketing of cigarettes and E-cigarettes as predictors of smoking cessation behaviors

The message for people who smoke combustible cigarettes is the same as always try to quit using tobacco and nicotine products and seek support from your physician and community to increase your chances of success. The CLUES Study was an observational, product challenge study