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Other measures At session onset, participants completed the 32-item Questionnaire on Smoking Urgers (QSU-32) 37 and the 21-item Withdrawal Symptom Checklist (WSC) 38 to ensure there were no differences by randomization conditions in baseline craving and withdrawal, respectively

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These result from the fact that the brain is used to having nicotine and it doesnt have it any more

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Government of Canada, 2020

[21] Secondly, the gut microbiota is crucial in maintaining digestive health, and smoking cessation could alter its composition