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When should anxiety linked to nicotine use be medically evaluated

Do it often enough to break the habit

The next largest, Pennsylvania, had under 500,000

JAMA (2018) 319:1431

The increased prevalence of illicit purchasing may represent a shift in purchasing pattern rather than a definitive increase in the overall size of the illicit market

Unregulated vaping products often exceed nicotine concentration limits, contain undisclosed ingredients or contaminants, and lack safety standards for packaging, labelling, and battery integrity