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E., Romagna, G., Tsiapras, D., Kyrzopoulos, S

Unlike the freebase nicotine in regular cigarettes, which can be very irritating, nicotine salt goes down smoothly and doesnt cause the unpleasant feeling in the chest and lungs that cigarette smoke does, said David Liddell Ashley, a former director of the office of science in the Center for Tobacco Products at the FDA

did not find a significant association among youth, but imply that there could be a true association that was not detected due to low statistical power [21])

While regulatory uncertainties persist in certain markets, the presence of an aspirational youth demographic offers significant potential for expansion