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Evidence level: Level E (case report hypothesis) and mechanistic plausibility

For a medication with documented cardiovascular benefits and a specific metabolic profile, that unknown should factor into your decision

While not an absolute contraindication, previous pancreatic inflammation increases the risk of recurrence with GLP-1 medications

[8] H2-receptor antagonists like famotidine for less severe symptoms

In conclusion, this first report demonstrated a successful desensitization protocol to exenatide in patients with isolated immediate skin reaction and local reactions and indicated the importance of desensitization in patients who do not have alternative therapies

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