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A gradual dose-escalation is recommended for liraglutide 3.0 mg, starting with the initial dose of 0.6 mg per day for 1 week, then increasing the dose in weekly increments until the maximum therapeutic dose of 3.0 mg is reached [21]

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However, your provider may recommend starting at a lower tirzepatide dose even if you are coming from a high semaglutide dose

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High-intensity interval training (HIIT) and heavy resistance training are also compatible with semaglutide, but introduce them gradually if you are new to structured exercise