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Semaglutide is a GLP-1 receptor agonist that targets one hormone receptor

Both preclinical and clinical researches (Table 2) have indicated significant glucose-lowering effects

For chronic weight management , NICE recommends tirzepatide only for adults with: A BMI of 35 kg/m or above with at least one weight-related comorbidity (such as hypertension, type 2 diabetes, dyslipidaemia, obstructive sleep apnoea, or cardiovascular disease) Lower BMI thresholds may apply for people from certain ethnic backgrounds, in line with NICE Clinical Guideline 189 on obesity management

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This figure represents 26.5% of all adults with diagnosed diabetes, a dramatic rise over a short study period

GLP-1 Analogues Market Regional Analysis North America Holds the Largest Share in the GLP-1 Analogues Market North America dominates the GLP-1 analogues market with an estimated market share of over 76.05%, primarily driven by high obesity and diabetes prevalence, strong healthcare infrastructure, and early adoption of innovative therapies U.S
