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Although improvements in the high-sensitivity C-reactive protein levels, insulin resistance and lipid profile were shown to be mediated by improvements in the AHI and hypoxic burden, the improvement in blood pressure control was not mediated by these factors

These benefits are critical, especially considering the role of obesity as a known risk factor in the development of type 2 diabetes and other chronic conditions

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Acceptable as long as the instruments used were single-use equipment and disposable (which means both the gun and the earring cassette were disposable)