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G49, a dual glucagon/glucagon-like peptide-1 receptor agonist, triggers an inter-organ crosstalk between adipose tissue, pancreas and liver, leading to brown fat activation with the final outcomes of increased energy expenditure and body weight loss.

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Restless leg syndrome (RLS) is a neurological disorder that can be extremely unpleasant to live with

60% of the weight comes back within a year of stopping GLP-1s
