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Adipose tissue functions as both insulation and an endocrine organ that influences metabolic rate

But sort of changing someone's identity, it sounds like, is a little bit the hack to keep that working

Ongoing TRANSCEND Phase 3 trials are evaluating retatrutide specifically for type 2 diabetes

But study participants taking the drug still lost significantly more weight than those under the same conditions who received a placebo

Adv Exp Med Biol (2019) 1184:187203