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Ozempic has now also been approved by the US Food and Drug Administration to reduce certain risks associated with chronic kidney disease, drugmaker Novo Nordisk said Tuesday.

Novo already sells an oral semaglutide for type 2 diabetes, Rybelsus

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Although long-term safety and efficacy require further evaluation, current evidence positions GLP-1 RAs as promising therapeutic agents in translational geroscience, with the potential to mitigate age-related physiological decline and promote a longer, healthier lifespan.

The diagnostic criteria for DKA typically include blood glucose above 250 mg/dL, arterial pH below 7.3, bicarbonate under 18 mEq/L, an elevated anion gap (greater than 10), and ketones above 3 mmol/L often much higher