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However, discontinuation is often followed by partial weight regain within months, reinforcing that patients generally experience these medicines as chronic therapies rather than short term cures

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5 Kapitza, C., et al., Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial

Combined with potential GI side effects, this may lead to fluid and electrolyte loss, making intentional hydration more important

Side effects are another important consideration

Most people have never heard of amylin, but it plays a critical role in how your body regulates appetite suppression and glucose metabolism
