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Notably, most of the differentially expressed phosphorylated proteins identified in this study were mainly involved in pathways of neurodegenerationmultiple diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease and amyotrophic lateral sclerosis, suggesting that high-fat diet-induced obesity may share a common molecular mechanism with the above diseases

Disclosures IQVIA, the employer of Hera Sandhu, Weiwei Xu, and Anamaria-Vera Olivieri received consulting fees from Novo Nordisk for conducting the analyses reported in this manuscript

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