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doi: 10.1111/dom.12854
I have been tracking data and decided to do a deep dive going back 5 yrs (Dec 2020 - Jan 2026) to see what I find

While the evidence regarding GLP-1 receptor expression in testosterone-producing tissues is limited and mixed in humans, the metabolic changes induced by semaglutideparticularly significant weight loss and improved insulin sensitivitycan indirectly affect hormone balance

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G lucagon- L ike P eptide-1 is a hormone that helps regulate hunger and appetite

A follow-up analysis was performed in which baseline and percentage change from baseline to week 68 (end of treatment) for both body weight and HbA 1c were included as additional covariates in the model
