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acylation to extend half-life, modifications to improve receptor selectivity or bias, PEGylation) are used to improve pharmacokinetics, dosing interval, and tolerability

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A 2024 retrospective analysis of 33,000 medical records of people with type 2 diabetes found patients who received the obesity drug Ozempic had roughly one-third to half the risk of overdosing on opioids compared to patients on other diabetes medications

Some people feel appetite suppression within a few weeks, but significant weight reduction takes time

That growth has already been enjoyed by shareholders of the companies dominating that space, including Novo Nordisk NYSE: NVO, maker of Ozempic and Wegovy, and Eli Lilly NYSE: LLY, maker of Zepound and Mounjaro

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