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Most people find that as they become more comfortable with the self-injection process, the frequency of these marks decreases

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Studies show that people who discontinue GLP-1 medications typically regain weight within several months

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Do not alter your dosing regimen or discontinue Ozempic without consulting your provider first

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Several factors increase your likelihood significantly: History of GERD or acid reflux , even if it was well-controlled before starting tirzepatide Hiatal hernia , which already weakens the lower esophageal sphincter Obesity , which increases abdominal pressure (though this improves as you lose weight on the medication) Smoking , which relaxes the esophageal sphincter Certain medications like NSAIDs, calcium channel blockers, or bisphosphonates that independently increase reflux risk Eating large meals or eating close to bedtime If you had occasional heartburn before starting tirzepatide, the medication can amplify it significantly during the early weeks

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However, it's important to note that some individuals start with semaglutide but switch to tirzepatide later on to capitalize on its superior weight management potential

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