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14 In healthy people, the gut bacterium Clostridium bolteae converts primary bile acids into ursodeoxycholic acid, which is then conjugated into glycoursodeoxycholic acid (GUDCA)

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This leads to neuroprotection of RGCs and helps preserve retinal function ( 2.2.2 ERK1/2-HDAC6 signaling pathway The GLP-1R-ERK1/2-HDAC6 signaling pathway complements the mitophagy pathway by modulating oxidative stress and autophagy

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10.1186/s12933-024-02461-2 11 ChenD.LiangH.HuangL.ZhouH.WangZ

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P.MiolaM.LuccaT.et al (1997)

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